Interesting series of videos by Jeff Jonas, "Mister Data" at IBM:
See also: http://en.wikipedia.org/wiki/Big_data
1. How to deal with huge volume of data? How to exploit it, understand trends, cycles, etc. ?
2. How to bring sense, meaning into that big data?
For #1, see Attivio, ClickFox or Aqumin for new technologies being able to nicely display huge amount of real-time data.
For #2, connect data together, build a context around it. It's all about semantics.